NMR resonance assignments of 18.5*kDa complex of Arabidopsis thaliana*DRB7.2:DRB4 interaction domains
NMR resonance assignments of 18.5*kDa complex of Arabidopsis thaliana*DRB7.2:DRB4 interaction domains
In higher eukaryotes, the dsRNA binding proteins (dsRBPs) assist the corresponding Dicer in the cleavage of dsRNA precursors to effect post-transcriptional gene regulation through RNA interference. In contrast, the DRB7.2:DRB4 complex in Arabidopsis thaliana acts as a potent inhibitor of Dicer-like 3 (DCL3) processing by sequestering endogenous inverted-repeat dsRNA precursors. DRB7.2 possesses a single dsRNA Binding Domain (dsRBD) flanked by unstructured N- and C-terminal regions. Whereas, DRB4... More... |
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