BioNMR
NMR aggregator & online community since 2003
BioNMR    
Learn or help to learn NMR - get free NMR books!
 

Go Back   BioNMR > Educational resources > Journal club
Advanced Search



Jobs Groups Conferences Literature Pulse sequences Software forums Programs Sample preps Web resources BioNMR issues


Webservers
NMR processing:
MDD
NMR assignment:
Backbone:
Autoassign
MARS
UNIO Match
PINE
Side-chains:
UNIO ATNOS-Ascan
NOEs:
UNIO ATNOS-Candid
UNIO Candid
ASDP
Structure from NMR restraints:
Ab initio:
GeNMR
Cyana
XPLOR-NIH
ASDP
UNIO ATNOS-Candid
UNIO Candid
Fragment-based:
BMRB CS-Rosetta
Rosetta-NMR (Robetta)
Template-based:
GeNMR
I-TASSER
Refinement:
Amber
Structure from chemical shifts:
Fragment-based:
WeNMR CS-Rosetta
BMRB CS-Rosetta
Homology-based:
CS23D
Simshift
Torsion angles from chemical shifts:
Preditor
TALOS
Promega- Proline
Secondary structure from chemical shifts:
CSI (via RCI server)
TALOS
MICS caps, β-turns
d2D
PECAN
Flexibility from chemical shifts:
RCI
Interactions from chemical shifts:
HADDOCK
Chemical shifts re-referencing:
Shiftcor
UNIO Shiftinspector
LACS
CheckShift
RefDB
NMR model quality:
NOEs, other restraints:
PROSESS
PSVS
RPF scores
iCing
Chemical shifts:
PROSESS
CheShift2
Vasco
iCing
RDCs:
DC
Anisofit
Pseudocontact shifts:
Anisofit
Protein geomtery:
Resolution-by-Proxy
PROSESS
What-If
iCing
PSVS
MolProbity
SAVES2 or SAVES4
Vadar
Prosa
ProQ
MetaMQAPII
PSQS
Eval123D
STAN
Ramachandran Plot
Rampage
ERRAT
Verify_3D
Harmony
Quality Control Check
NMR spectrum prediction:
FANDAS
MestReS
V-NMR
Flexibility from structure:
Backbone S2
Methyl S2
B-factor
Molecular dynamics:
Gromacs
Amber
Antechamber
Chemical shifts prediction:
From structure:
Shiftx2
Sparta+
Camshift
CH3shift- Methyl
ArShift- Aromatic
ShiftS
Proshift
PPM
CheShift-2- Cα
From sequence:
Shifty
Camcoil
Poulsen_rc_CS
Disordered proteins:
MAXOCC
Format conversion & validation:
CCPN
From NMR-STAR 3.1
Validate NMR-STAR 3.1
NMR sample preparation:
Protein disorder:
DisMeta
Protein solubility:
camLILA
ccSOL
Camfold
camGroEL
Zyggregator
Isotope labeling:
UPLABEL
Solid-state NMR:
sedNMR


Reply
Thread Tools Search this Thread Rate Thread Display Modes
  #1  
Unread 06-25-2016, 03:16 PM
nmrlearner's Avatar
Senior Member
 
Join Date: Jan 2005
Posts: 23,135
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 193,617
Downloads: 0
Uploads: 0
Default NMR Meets Tau: Insights into Its Function and Pathology.

NMR Meets Tau: Insights into Its Function and Pathology.

NMR Meets Tau: Insights into Its Function and Pathology.

Biomolecules. 2016;6(2)

Authors: Lippens G, Landrieu I, Smet C, Huvent I, Gandhi NS, Gigant B, Despres C, Qi H, Lopez J

Abstract
In this review, we focus on what we have learned from Nuclear Magnetic Resonance (NMR) studies on the neuronal microtubule-associated protein Tau. We consider both the mechanistic details of Tau: the tubulin relationship and its aggregation process. Phosphorylation of Tau is intimately linked to both aspects. NMR spectroscopy has depicted accurate phosphorylation patterns by different kinases, and its non-destructive character has allowed functional assays with the same samples. Finally, we will discuss other post-translational modifications of Tau and its interaction with other cellular factors in relationship to its (dys)function.


PMID: 27338491 [PubMed - in process]



More...
Reply With Quote


Did you find this post helpful? Yes | No

Reply
Similar Threads
Thread Thread Starter Forum Replies Last Post
[NMR paper] The N-terminal ubiquitin-binding region of ubiquitin-specific protease 28 modulates its deubiquitination function: NMR structural and mechanistic insights.
The N-terminal ubiquitin-binding region of ubiquitin-specific protease 28 modulates its deubiquitination function: NMR structural and mechanistic insights. http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--highwire.stanford.edu-icons-externalservices-pubmed-highwire.gif Related Articles The N-terminal ubiquitin-binding region of ubiquitin-specific protease 28 modulates its deubiquitination function: NMR structural and mechanistic insights. Biochem J. 2015 Oct 15;471(2):155-65 Authors: Wen Y, Shi L, Ding Y, Cui R, He WT, Hu HY,...
nmrlearner Journal club 0 01-01-2016 05:03 PM
Postdoctoral Research Associate in Pathology and Laboratory Medicine at UNC - Chapel Hill
This position, in the lab of David C Williams Jr, MD, PhD, will involve NMR analysis of the structure and dynamics of protein-DNA complexes. The work will include DNA cloning, isotopically labeled protein expression, and extensive NMR data collection and analysis. Applicants should have a PhD degree in biological or chemical sciences plus experience with NMR spectroscopy and structure determination is required. Proficiency in DNA cloning and protein expression is expected. Applicants should apply online at http://unc.peopleadmin.com/postings/42205 and attach a cover letter, curriculum...
dcwilljr Job marketplace 0 04-23-2014 01:46 PM
[NMR paper] Insights into hERG K+ channel structure and function from NMR studies.
Insights into hERG K+ channel structure and function from NMR studies. http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--production.springer.de-OnlineResources-Logos-springerlink.gif Related Articles Insights into hERG K+ channel structure and function from NMR studies. Eur Biophys J. 2013 Jan;42(1):71-9 Authors: Ng CA, Torres AM, Pagès G, Kuchel PW, Vandenberg JI Abstract The unique gating kinetics of hERG K(+) channels are critical for normal cardiac repolarization, and patients with mutations in hERG have a...
nmrlearner Journal club 0 06-15-2013 09:13 PM
Handheld cancer detection: Microfluidics meets NMR
Handheld cancer detection: Microfluidics meets NMR http://www.spectroscopynow.com/common/images/thumbnails/13ef060ff6a.jpgA handheld device first developed for cancer diagnosis has been adapted to rapidly diagnose tuberculosis (TB) and other bacterial infections. Two papers appearing in the journals Nature Communications and Nature Nanotechnology describe the portable systems that bring together microfluidics technology and NMR. Read the rest at Spectroscopynow.com
nmrlearner General 0 06-01-2013 02:03 PM
When detergent meets bilayer: birth and coming of age of lipid bicelles
When detergent meets bilayer: birth and coming of age of lipid bicelles Available online 23 January 2013 Publication year: 2013 Source:Progress in Nuclear Magnetic Resonance Spectroscopy</br> </br> Graphical abstract
nmrlearner Journal club 0 01-24-2013 09:57 AM
[NMRpipe Yahoo group] Re: MED function error.
Re: MED function error. Hi Jason, Thanks very much for bringing this problem to my attention ... sorry, I (yes, even I) made what we call in the trade a "+ 1" "- 1" kind of mistake More...
NMRpipe Yahoo group news News from other NMR forums 0 07-05-2012 04:13 AM
[NMRpipe Yahoo group] MED function error.
MED function error. Dear Frank, We are experiencing segmentation faults in recent versions of NMRPipe on Mac OS X (10.6.8) when using the MED function. An example 2D processing More...
NMRpipe Yahoo group news News from other NMR forums 0 07-04-2012 01:08 AM
[NMR analysis blog] Micropost [OT]: NMR meets Football
Micropost : NMR meets Football http://2.bp.blogspot.com/_-MfflvAgRls/SwUfZ413_FI/AAAAAAAAAgk/SY9PjMIRoDQ/s400/NMRBalls.jpg Relaxation plays a major role in NMR spectroscopy – What’s better than playing sports to chill out and forget about everyday problems? I reckon this is not the best football team you might find but at least I guarantee they are fun people (sponsored by a great company :-) ) with whom you can have a good time (and get a free t-shirt!) :-) Mestrelab World of Sports - Free Mnova t-shirt quiz
nmrlearner News from NMR blogs 0 08-21-2010 09:12 PM


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes Rate This Thread
Rate This Thread:

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is On
Trackbacks are Off
Pingbacks are Off
Refbacks are Off



BioNMR advertisements to pay for website hosting and domain registration. Nobody does it for us.



Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Copyright, BioNMR.com, 2003-2013
Search Engine Friendly URLs by vBSEO 3.6.0

All times are GMT. The time now is 07:23 AM.


Map