NMR imprint of intersubunit communication [Biophysics and Computational Biology]
 

NMR imprint of intersubunit communication [Biophysics and Computational Biology]

Falk, B. T., Sapienza, P. J., Lee, A. L....
Date: 2016-08-23

Allosteric communication is critical for protein function and cellular homeostasis, and it can be exploited as a strategy for drug design. However, unlike many protein–ligand interactions, the structural basis for the long-range communication that underlies allostery is not well understood. This lack of understanding is most evident in the case... Read More


PNAS:
Number: 34
Volume: 113