NMR analysis of low-density lipoprotein oxidatively-modified in vitro.
 

NMR analysis of low-density lipoprotein oxidatively-modified in vitro.

Related Articles NMR analysis of low-density lipoprotein oxidatively-modified in vitro.

Free Radic Res Commun. 1990;8(3):175-83

Authors: Barenghi L, Bradamante S, Giudici GA, Vergani C

Human plasma low density lipoprotein has been oxidized at different stages in vitro and analysed by 1H, 13C, and 31P NMR spectroscopy and by biochemical methods. Information was obtained on: a) structure mobilities of lipids and on lipid-protein interactions; b) conjugated and oxo-dienes; c) polyunsaturated/monounsaturated fatty acid chains; d) lysophosphatidylcholine production. The results show that the NMR approach is particularly useful for the assessment of structural modification in oxidized LDL.

PMID: 2328928 [PubMed - indexed for MEDLINE]



Source: PubMed