New perceptions of transcription factor properties from NMR.
 

New perceptions of transcription factor properties from NMR.

Related Articles New perceptions of transcription factor properties from NMR.

Biochem Cell Biol. 1998;76(2-3):368-78

Authors: Bagby S, Arrowsmith CH, Ikura M

The complementarity of NMR and X-ray crystallography for biomacromolecular studies has been particularly evident in analysis of transcription factor structures and interactions. While X-ray crystallography can be used to tackle relatively complicated structural problems including multicomponent (three and higher) complexes, NMR studies have provided new insights into the nature of protein-DNA and protein-protein interactions that would be difficult to obtain by other biophysical methods. We describe herein some of the novel and important information recently derived from NMR studies of transcription factors.

PMID: 9923706 [PubMed - indexed for MEDLINE]



Source: PubMed