Multiplexing NMR experiments by direct detection of multiple free induction decays (FIDs) in a single experiment offers a dramatic increase in the spectral information content and often yields significant improvement in sensitivity per unit time. Experiments with multi-FID detection have been designed with both homonuclear and multinuclear acquisition, and the advent of multiple receivers on commercial spectrometers opens up new possibilities for recording spectra from different nuclear species...
Multi-receiver solid-state NMR using polarization optimized experiments (POE) at ultrafast magic angle spinning
Multi-receiver solid-state NMR using polarization optimized experiments (POE) at ultrafast magic angle spinning
Abstract
Ultrafast magic angle spinning (MAS) technology and 1H detection have dramatically enhanced the sensitivity of solid-state NMR (ssNMR) spectroscopy of biopolymers. We previously showed that, when combined with polarization optimized experiments (POE), these advancements enable the simultaneous acquisition of multi-dimensional 1H- or 13C-detected experiments using a single receiver. Here, we propose a new sub-class within the POE...
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04-25-2020 12:56 PM
NMR-STAR: comprehensive ontology for representing, archiving and exchanging data from nuclear magnetic resonance spectroscopic experiments
NMR-STAR: comprehensive ontology for representing, archiving and exchanging data from nuclear magnetic resonance spectroscopic experiments
Abstract
The growth of the biological nuclear magnetic resonance (NMR) field and the development of new experimental technology have mandated the revision and enlargement of the NMR-STAR ontology used to represent experiments, spectral and derived data, and supporting metadata. We present here a brief description of the NMR-STAR ontology and software tools for manipulating NMR-STAR data files, editing the files,...
nmrlearner
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01-07-2019 05:49 AM
A tailored multi-frequency EPR approach to accurately determine the magnetic resonance parameters of dynamic nuclear polarization agents: application to AMUPol #DNPNMR
From The DNP-NMR Blog:
A tailored multi-frequency EPR approach to accurately determine the magnetic resonance parameters of dynamic nuclear polarization agents: application to AMUPol #DNPNMR
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This is a very nice article illustrating the importance of understanding the EPR parameters of a polarizing agent used in DNP-NMR spectroscopy. Here the 9, 95 and 275 GHz EPR spectroscopy is used to characterize AMUPol and predict its performance in high-field DNP.
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06-05-2017 03:59 PM
Dynamic nuclear polarisation via the integrated solid effect II: experiments on naphthalene-h8doped with pentacene-d14 #DNPNMR
From The DNP-NMR Blog:
Dynamic nuclear polarisation via the integrated solid effect II: experiments on naphthalene-h8doped with pentacene-d14 #DNPNMR
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Eichhorn, T.R., et al., Dynamic nuclear polarisation via the integrated solid effect II: experiments on naphthalene-h8doped with pentacene-d14. Mol. Phys., 2013. 112(13): p. 1773-1782.
https://doi.org/10.1080/00268976.2013.863405
Dynamic nuclear polarization experiments at 14.1 T for solid-state NMR.
Dynamic nuclear polarization experiments at 14.1 T for solid-state NMR.
Related Articles Dynamic nuclear polarization experiments at 14.1 T for solid-state NMR.
Phys Chem Chem Phys. 2010 Jun 14;12(22):5799-803
Authors: Matsuki Y, Takahashi H, Ueda K, Idehara T, Ogawa I, Toda M, Akutsu H, Fujiwara T
Instrumentation for high-field dynamic nuclear polarization (DNP) at 14.1 T was developed to enhance the nuclear polarization for NMR of solids. The gyrotron generated 394.5 GHz submillimeter (sub-mm) wave with a power of 40 W in the second harmonic...
nmrlearner
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08-26-2010 04:41 PM
[NMR paper] Study on the erythrocytes from myotonic dystrophy with multi-nuclear NMR.
Study on the erythrocytes from myotonic dystrophy with multi-nuclear NMR.
Related Articles Study on the erythrocytes from myotonic dystrophy with multi-nuclear NMR.
Muscle Nerve. 1991 Jan;14(1):57-63
Authors: Kuwabara T, Yuasa T, Ohno T, Yamamuro M, Miyatake T
We have studied the water permeability through membranes, the function of the Na pump, and glucose metabolism of erythrocytes of patients with myotonic muscular dystrophy (MyD) using 1H--, 23Na, and 13C-NMR techniques. A significant decrease in water permeability was recognized in the...
nmrlearner
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08-21-2010 11:16 PM
Nitrogen-detected CAN and CON experiments as alternative experiments for main chain N
Abstract Heteronuclear direct-detection experiments, which utilize the slower relaxation properties of low γ nuclei, such as 13C have recently been proposed for sequence-specific assignment and structural analyses of large, unstructured, and/or paramagnetic proteins. Here we present two novel 15N direct-detection experiments. The CAN experiment sequentially connects amide 15N resonances using 13Cα chemical shift matching, and the CON experiment connects the preceding 13C� nuclei. When starting from the same carbon polarization, the intensities of nitrogen signals detected in the CAN or...
Multiplexing experiments in NMR and multi-nuclear MRI
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