Methyl-TROSY NMR studies of proteasome allostery [Biophysics and Computational Biology]
 

Methyl-TROSY NMR studies of proteasome allostery [Biophysics and Computational Biology]

Ruschak, A. M., Kay, L. E....
Date: 2012-12-11

Protein degradation plays a critical role in cellular homeostasis, in regulating the cell cycle, and in the generation of peptides that are used in the immune response. The 20S proteasome core particle (CP), a barrel-like structure consisting of four heptameric protein rings stacked axially on top of each other, is... Read More


PNAS:
Number: 50
Volume: 109