BioNMR

BioNMR (http://www.bionmr.com/forum/)
-   Journal club (http://www.bionmr.com/forum/journal-club-9/)
-   -   [NMR paper] Longitudinal Spin Order Labeling on Multiple Quantum Coherences Enables NMR Analysis of Intrinsically Disordered Proteins at Ultrahigh Resolution (http://www.bionmr.com/forum/journal-club-9/longitudinal-spin-order-labeling-multiple-quantum-coherences-enables-nmr-analysis-intrinsically-disordered-proteins-ultrahigh-resolution-28567/)

nmrlearner 09-21-2021 06:03 PM

Longitudinal Spin Order Labeling on Multiple Quantum Coherences Enables NMR Analysis of Intrinsically Disordered Proteins at Ultrahigh Resolution
 
Longitudinal Spin Order Labeling on Multiple Quantum Coherences Enables NMR Analysis of Intrinsically Disordered Proteins at Ultrahigh Resolution

Intrinsically disordered proteins (IDPs) play an important role in cell signaling, and NMR is well-suited to study conformational ensembles and dynamics of IDPs. However, the intrinsic flexibility of IDPs often results in severe spectral overlap, which hampers accurate NMR data analysis. By labeling the longitudinal spin order of an ? proton (i.e., H^(?)(z)) on multiple quantum coherences of backbone nuclei (e.g., N(y)C'(x)C^(?)(y)), we were able to apply pre-homonuclear decoupling (PHD) to...

More...


All times are GMT. The time now is 09:00 PM.

Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Search Engine Friendly URLs by vBSEO 3.6.0
Copyright, BioNMR.com, 2003-2013