Interactions of HIV gp41's membrane-proximal external region and transmembrane domain with phospholipid membranes from (31)P NMR
 

Interactions of HIV gp41's membrane-proximal external region and transmembrane domain with phospholipid membranes from (31)P NMR

HIV-1 entry into cells requires coordinated changes of the conformation and dynamics of both the fusion protein, gp41, and the lipids in the cell membrane and virus envelope. Commonly proposed features of membrane deformation during fusion include high membrane curvature, lipid disorder, and membrane surface dehydration. The virus envelope and target cell membrane contain a diverse set of phospholipids and cholesterol. To dissect how different lipids interact with gp41 to contribute to membrane...

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