Insights into the Structure and Dynamics of Measles Virus Nucleocapsids by (1)H-detected Solid-state NMR.
 

Insights into the Structure and Dynamics of Measles Virus Nucleocapsids by (1)H-detected Solid-state NMR.

Related Articles Insights into the Structure and Dynamics of Measles Virus Nucleocapsids by (1)H-detected Solid-state NMR.

Biophys J. 2014 Aug 19;107(4):941-946

Authors: Barbet-Massin E, Felletti M, Schneider R, Jehle S, Communie G, Martinez N, Jensen MR, Ruigrok RW, Emsley L, Lesage A, Blackledge M, Pintacuda G

Abstract
(1)H-detected solid-state nuclear magnetic resonance (NMR) experiments are recorded on both intact and trypsin-cleaved sedimented measles virus (MeV) nucleocapsids under ultra-fast magic-angle spinning. High-resolution (1)H,(15)N-fingerprints allow probing the degree of molecular order and flexibility of individual capsid proteins, providing an exciting atomic-scale complement to electro microscopy (EM) studies of the same systems.


PMID: 25140429 [PubMed - as supplied by publisher]



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