HIV-1 leader RNA dimeric interface revealed by NMR [Biophysics and Computational Biology]
 

HIV-1 leader RNA dimeric interface revealed by NMR [Biophysics and Computational Biology]

Laura R. Ganser, Hashim M. Al-Hashimi...
Date: 2016-11-22

The genomes of retroviruses, such as HIV, consist of two single-stranded RNAs held together as a dimer through noncovalent interactions near the 5?-end. Why retroviruses carry two copies of their genetic material when most other viruses carry a single copy is something of a mystery. The single-stranded genomic RNA (gRNA)... Read More


PNAS:
Number: 47
Volume: 113