Highly selective excitation in biomolecular NMR by frequency-switched single-transiti
 

Highly selective excitation in biomolecular NMR by frequency-switched single-transition cross-polarization.

Related Articles Highly selective excitation in biomolecular NMR by frequency-switched single-transition cross-polarization.

J Am Chem Soc. 2002 Mar 13;124(10):2076-7

Authors: Ferrage F, Eykyn TR, Bodenhausen G

A new method for selective excitation in biomolecular NMR uses two-fold single-transition cross-polarization between protons and nitrogen-15 or carbon-13 nuclei. Switching the frequencies between the forward and backward transfer steps allows one to select a multiplet pattern that is associated with a single pair of spins in a medium-size protein. The efficiency of the transfer benefits from so-called TROSY line-narrowing effects which arise from interference between relaxation mechanisms.

PMID: 11878936 [PubMed - indexed for MEDLINE]



Source: PubMed