High-dimensional NMR methods for intrinsically disordered proteins studies.
High-dimensional NMR methods for intrinsically disordered proteins studies.
Related Articles High-dimensional NMR methods for intrinsically disordered proteins studies. Methods. 2018 Apr 26;: Authors: Grudzi?? K, Zawadzka-Kazimierczuk A, Ko?mi?ski W Abstract Intrinsically disordered proteins (IDPs) are getting more and more interest of the scientific community. Nuclear magnetic resonance (NMR) is often a technique of choice for these studies, as it provides atomic-resolution information on structure, dynamics and interactions of IDPs. Nonetheless, NMR spectra of IDPs are typically extraordinary crowded, comparing to those of structured proteins. To overcome this problem, high-dimensional NMR experiments can be used, which allow for a better peak separation. In the present review different aspects of such experiments are discussed, from data acquisition and processing to analysis, focusing on experiments for resonance assignment. PMID: 29705209 [PubMed - as supplied by publisher] More... |
All times are GMT. The time now is 07:24 AM. |
Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Search Engine Friendly URLs by vBSEO 3.6.0
Copyright, BioNMR.com, 2003-2013