Efficient assignment and NMR analysis of an intact virus using sequential side-chain correlations and DNP sensitization [Biophysics and Computational Biology]
 

Efficient assignment and NMR analysis of an intact virus using sequential side-chain correlations and DNP sensitization [Biophysics and Computational Biology]

Ivan V. Sergeyev, Boris Itin, Rivkah Rogawski, Loren A. Day, Ann E. McDermott...
Date: 2017-05-16

An experimental strategy has been developed to increase the efficiency of dynamic nuclear polarization (DNP) in solid-state NMR studies. The method makes assignments simpler, faster, and more reliable via sequential correlations of both side-chain and C? resonances. The approach is particularly suited to complex biomolecules and systems with significant chemical-shift... Read More


PNAS:
Number: 20
Volume: 114