Direct detection of lysine side chain NH3+ in protein-heparin complexes using NMR spectroscopy.
Direct detection of lysine side chain NH3+ in protein-heparin complexes using NMR spectroscopy.
http://www.bionmr.com//www.ncbi.nlm...._z_RSClogo.gif Related Articles Direct detection of lysine side chain NH3+ in protein-heparin complexes using NMR spectroscopy. Analyst. 2018 Jan 02;: Authors: Sepuru KM, Iwahara J, Rajarathnam K Abstract Two NMR observables, the N?H3+ peak in the HISQC spectrum and N? chemical shift difference between the free and heparin-bound forms, can identify binding-interface lysines in protein-heparin complexes. Unlike backbone chemical shifts, these direct probes are stringent and are less prone to either false positives or false negatives. PMID: 29292440 [PubMed - as supplied by publisher] More... |
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