Design of Highly Fluorinated Peptides for Cell-based 19F NMR
 

Design of Highly Fluorinated Peptides for Cell-based 19F NMR

The design of imaging agents with high fluorine content is essential for overcoming the challenges associated with signal detection limits in ^(19)F MRI-based molecular imaging. In addition to perfluorocarbon and fluorinated polymers, fluorinated peptides offer an additional strategy for creating sequence-defined ^(19)F magnetic resonance imaging (MRI) imaging agents with a high fluorine signal. Our previously reported unstructured trifluoroacetyllysine-based peptides possessed good...

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