Current Applications of 19F NMR to Studies of Protein Structure and Dynamics
 

Current Applications of 19F NMR to Studies of Protein Structure and Dynamics


Publication year: 2011
Source: Progress in Nuclear Magnetic Resonance Spectroscopy, In Press, Accepted Manuscript, Available online 13 July 2011</br>
Julianne L., Kitevski-LeBlanc , R., Scott Prosser</br>
*Highlights:*? 19F molecular tags and labelling protocols for 19F NMR studies of proteins are reviewed and contrasted. ? 19F NMR biosynthetic labelling strategies are presented. ? Experimental challenges (loss of function through labelling, line broadening, assignment ambiguities) are discussed. ? Approaches to the study of protein topology, using 19F NMR, are presented. ? Current examples of protein NMR studies are given.</br></br>

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