Analysis of protein-ligand interactions from titrations and NMR relaxation dispersions
 

Analysis of protein-ligand interactions from titrations and NMR relaxation dispersions

We present PLIS, a publicly available, open-source software for the determination of protein-ligand dissociation constants that can be used to characterize biological processes or to shed light on biophysical aspects of interactions. PLIS can analyze data from titration experiments monitored by for instance fluorescence spectroscopy or from nuclear magnetic resonance relaxation dispersion experiments. In addition to analysis of experimental data, PLIS includes functionality for generation of...

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