(19)F NMR as a tool in chemical biology
 

(19)F NMR as a tool in chemical biology

We previously reviewed the use of ^(19)F NMR in the broad field of chemical biology [Cobb, S. L.; Murphy, C. D. J. Fluorine Chem. 2009, 130, 132-140] and present here a summary of the literature from the last decade that has the technique as the central method of analysis. The topics covered include the synthesis of new fluorinated probes and their incorporation into macromolecules, the application of ^(19)F NMR to monitor protein-protein interactions, protein-ligand interactions,...

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