Postdoctoral position at FDA

[kangchen]

Source Code DPA 1313. The Food and Drug Administration, the Division of Pharmaceutical Analysis is recruiting a post-doctoral fellow for a one year temporary position at the White Oak facility in Silver Spring, Maryland laboratory. The initial appointment is for one year, but may be renewed upon recommendation of FDA contingent on the availability of funds.
Under the guidance of a mentor, the selected fellow will conduct research on generic drugs using nuclear magnetic resonance (NMR) methods. This research will aim to develop validated methods to assess the identity, purity and content of generic drugs in comparison to the reference listed drug. The participant will conduct analysis and experimentation in the laboratory utilizing prescribed procedures (protocols, standard operating procedures, etc.), and will document and report data in a timely manner according to regulatory guidelines. S/he will perform much of their research on a newly installed 850 MHz Bruker spectrometer equipped with a cold probe in the FDA White Oak Campus NMR Facility.
The Research Participation Program for FDA is administered by the Oak Ridge Institute for Science and Education (ORISE). The participant will receive a monthly stipend depending on educational level and experience. Proof of insurance must be provided to participate in this program. The appointment is full-time at FDA in the Silver Spring, Maryland, area. Participants do not become employees of FDA or the program administrator, and there are no fringe benefits paid.
At the end of the training period the fellow is expected to be able to independently work or advise on high-order structure validation/comparison of generic drugs using solution state NMR approaches.

• A Doctoral degree in analytical chemistry, pharmaceutical science, biopharmaceutics, biochemistry or biophysics, received within the last five years.
• Experience in the field of NMR structure analysis of small molecules or proteins is necessary.
• Experience with high field Bruker NMR spectrometers and multivariate statistical analysis of NMR data sets is highly desirable.
• Programming skills in object-oriented computer languages and shell scripts are highly desirable.
• Scientific writing skill is highly desirable.
• Knowledge of multi-dimension NMR and relaxation principles is desirable.
• Salary is commensurate with education and experience. US citizenship, green card, EAD, OPT or CPT is required. An H1 or J1 visa cannot be sponsored for this position.

How to apply: Submit CV to Kimberly Brammeier with cover letter by Email. Please indicate Source Code DPA1313 in the Subject line. Email by June 30, 2014 to: Kimberly.Brammeier@fda.hhs.gov