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NMR processing:
MDD
NMR assignment:
Backbone:
Autoassign
MARS
UNIO Match
PINE
Side-chains:
UNIO ATNOS-Ascan
NOEs:
UNIO ATNOS-Candid
UNIO Candid
ASDP
Structure from NMR restraints:
Ab initio:
GeNMR
Cyana
XPLOR-NIH
ASDP
UNIO ATNOS-Candid
UNIO Candid
Fragment-based:
BMRB CS-Rosetta
Rosetta-NMR (Robetta)
Template-based:
GeNMR
I-TASSER
Refinement:
Amber
Structure from chemical shifts:
Fragment-based:
WeNMR CS-Rosetta
BMRB CS-Rosetta
Homology-based:
CS23D
Simshift
Torsion angles from chemical shifts:
Preditor
TALOS
Promega- Proline
Secondary structure from chemical shifts:
CSI (via RCI server)
TALOS
MICS caps, β-turns
d2D
PECAN
Flexibility from chemical shifts:
RCI
Interactions from chemical shifts:
HADDOCK
Chemical shifts re-referencing:
Shiftcor
UNIO Shiftinspector
LACS
CheckShift
RefDB
NMR model quality:
NOEs, other restraints:
PROSESS
PSVS
RPF scores
iCing
Chemical shifts:
PROSESS
CheShift2
Vasco
iCing
RDCs:
DC
Anisofit
Pseudocontact shifts:
Anisofit
Protein geomtery:
Resolution-by-Proxy
PROSESS
What-If
iCing
PSVS
MolProbity
SAVES2 or SAVES4
Vadar
Prosa
ProQ
MetaMQAPII
PSQS
Eval123D
STAN
Ramachandran Plot
Rampage
ERRAT
Verify_3D
Harmony
Quality Control Check
NMR spectrum prediction:
FANDAS
MestReS
V-NMR
Flexibility from structure:
Backbone S2
Methyl S2
B-factor
Molecular dynamics:
Gromacs
Amber
Antechamber
Chemical shifts prediction:
From structure:
Shiftx2
Sparta+
Camshift
CH3shift- Methyl
ArShift- Aromatic
ShiftS
Proshift
PPM
CheShift-2- Cα
From sequence:
Shifty
Camcoil
Poulsen_rc_CS
Disordered proteins:
MAXOCC
Format conversion & validation:
CCPN
From NMR-STAR 3.1
Validate NMR-STAR 3.1
NMR sample preparation:
Protein disorder:
DisMeta
Protein solubility:
camLILA
ccSOL
Camfold
camGroEL
Zyggregator
Isotope labeling:
UPLABEL
Solid-state NMR:
sedNMR


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Unread 09-11-2010, 07:19 PM
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Default Post-doc in biomolecular NMR - CONCO

Post-doc in biomolecular NMR - CONCO

Description of the Faculty / Research group
The Faculty of Science consists of six departments: Biology, Pharmaceutical Sciences, Information and Computing Sciences, Physics and Astronomy, Mathematics and Chemistry. The Faculty is home to 3500 students and nearly 2000 staff and is internationally renowned for the quality of its research.
The NMR Research Group, headed by Prof. R. Boelens, is part of the Chemistry Department and belongs to the Bijvoet Center for Biomolecular Research. The research within the NMR group is focused on the structure determination of proteins and protein complexes by high-resolution NMR spectroscopy and bio-computational modelling. The group has strong research lines on protein-DNA and protein-protein complexes in transcription and DNA repair and modelling of bio-molecular complexes. The NMR Research group also belongs to the European NMR Research Infrastructures, providing experimental NMR access to European groups.
We are searching for a post-doc in biomolecular NMR.
Job description
You will be part of an international team using advanced post-genomic techniques for the discovery and development of new therapeutically relevant molecules issued from the venomous marine cone snail species Conus consors, a project funded under the 6th framework programme of the European Union (Contract no. LSHB-CT-2007-037591 – CONCO) (see also CONCO ). Your role in this project will be to apply both solution and solid-state NMR methods for the characterization of small snail toxins and their interaction with membrane receptors.
Qualifications
You should have a Ph.D. degree in chemistry, physics, bioinformatics, structural biology or a related field. You should possess a strong research background in biomolecular NMR (solution and/or solide-state) with experience in the collection and interpretation of NMR data, and are expected to show initiative and be able to work independently.
Terms of employment
The position on this project is available for a maximum of two years. Salary is dependent on qualifications and experience and ranges from €2802.- to €3678.- gross per month (salary scale 10). The salary is supplemented with a holiday bonus of 8% per year and a year-end bonus of 6.4% per year. We also offer a pension scheme. Employment conditions are according to the Collective Labour Agreement of Dutch Universities.
Further details

For further information contact Prof. Rolf Boelens (Phone: +31-30-2534035 Fax: +31-30-2537623 Email: r.boelens@uu.nl).
How to apply
Your application, referring to vacancynumber 65816, including a CV with contact information of two referees, should be sent to Science.PenO@uu.nl or: Faculty of Science, Personnel department, PO Box 80010, 3508 TA Utrecht.
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