Screening of dozens of strains of fungi that infect insects has led to the discovery of a strong inhibitor for the enzyme tyrosinase. Tyrosinase activity is involved in insect development processes but also in human aging, the development of melanoma, wound healing, and even in the browning of fruits and vegetables.
[NMR paper] Effects of J couplings and unobservable minor states on kinetics parameters extracted from CEST data
Effects of J couplings and unobservable minor states on kinetics parameters extracted from CEST data
Publication date: Available online 31 October 2014
Source:Journal of Magnetic Resonance</br>
Author(s): Yang Zhou , Daiwen Yang</br>
Chemical Exchange Saturation Transfer (CEST) experiments have emerged as a powerful tool for characterizing dynamics and sparse populated conformers of protein in slow exchanging systems. We show that J couplings and ‘invisible’ minor states can cause systematic errors in kinetics parameters and chemical shifts extracted from CEST...
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11-14-2014 08:33 AM
Reversed-Phase LC Isolates Potent Insecticidal Protein From Tarantula - LCGC Chromatography Online
Reversed-Phase LC Isolates Potent Insecticidal Protein From Tarantula - LCGC Chromatography Online
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LCGC Chromatography Online
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Reversed-Phase LC Isolates Potent Insecticidal Protein From Tarantula
LCGC Chromatography Online
The structure of the peptide, was determined by nuclear magnetic resonance (NMR) spectroscopy and indicated high thermal and chemical stability. According to the paper, this suggests the potential to...
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10-03-2013 03:31 PM
[NMR paper] Rapid screening and identification of ?-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR.
Rapid screening and identification of ?-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-2250-98-WileyOnlineLibrary-Button_120x27px_FullText.gif Related Articles Rapid screening and identification of ?-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR.
Biomed Chromatogr. 2013 Feb;27(2):148-55
Authors: Tao Y, Zhang Y, Cheng Y, Wang Y
...
[NMR paper] PA1b, an insecticidal protein extracted from pea seeds (Pisum sativum): 1H-2-D NMR st
PA1b, an insecticidal protein extracted from pea seeds (Pisum sativum): 1H-2-D NMR study and molecular modeling.
Related Articles PA1b, an insecticidal protein extracted from pea seeds (Pisum sativum): 1H-2-D NMR study and molecular modeling.
Biochemistry. 2003 Oct 21;42(41):11915-23
Authors: Jouvensal L, Quillien L, Ferrasson E, Rahbé Y, Guéguen J, Vovelle F
PA1b (pea albumin 1, subunit b) is a 37-amino acid cysteine-rich plant defense protein isolated from pea seeds (Pisum sativum). It induces short-term mortality in several pests, among...
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11-24-2010 09:16 PM
[NMR paper] NMR structure of cysteinyl-phosphorylated enzyme IIB of the N,N'-diacetylchitobiose-s
NMR structure of cysteinyl-phosphorylated enzyme IIB of the N,N'-diacetylchitobiose-specific phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli.
Related Articles NMR structure of cysteinyl-phosphorylated enzyme IIB of the N,N'-diacetylchitobiose-specific phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli.
J Mol Biol. 2001 May 18;308(5):993-1009
Authors: Ab E, Schuurman-Wolters GK, Nijlant D, Dijkstra K, Saier MH, Robillard GT, Scheek RM
The determination by NMR of the solution structure of the...
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11-19-2010 08:32 PM
[NMR paper] Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis.
Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis.
Related Articles Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis.
J Med Chem. 1999 Sep 23;42(19):3852-9
Authors: Hajduk PJ, Dinges J, Schkeryantz JM, Janowick D, Kaminski M, Tufano M, Augeri DJ, Petros A, Nienaber V, Zhong P, Hammond R, Coen M, Beutel B, Katz L, Fesik SW
The Erm family of methyltransferases confers resistance to the macrolide-lincosamide-streptogramin type B (MLS) antibiotics through the methylation of 23S ribosomal RNA. Upon...
Insecticidal fungi: Enzyme inhibitors extracted
Screening of dozens of strains of fungi that infect insects has led to the discovery of a strong inhibitor for the enzyme tyrosinase. Tyrosinase activity is involved in insect development processes but also in human aging, the development of melanoma, wound healing, and even in the browning of fruits and vegetables.
Linear Mode
