Discovering the secrets of collagen, a major component of connective tissue in mammals could lead to improved tissue engineering and cosmetic and reconstructive medicine. Researchers at Rice University have now used NMR spectroscopy to demonstrate how model collagen fibres self-assemble via their sticky ends.
[NMR paper] Water scaffolding in collagen: Implications on protein dynamics as revealed by solid-state NMR.
Water scaffolding in collagen: Implications on protein dynamics as revealed by solid-state NMR.
Water scaffolding in collagen: Implications on protein dynamics as revealed by solid-state NMR.
Biopolymers. 2013 Jun 19;
Authors: Aliev AE, Courtier-Murias D
Abstract
Solid-state NMR studies of collagen samples of various origin confirm that the amplitude of collagen backbone and sidechain motions increases significantly on increasing the water content. This conclusion is supported by the changes observed in three different NMR...
nmrlearner
Journal club
0
06-21-2013 01:10 PM
[NMR paper] Monomer-collagen interactions studied by saturation transfer difference NMR.
Monomer-collagen interactions studied by saturation transfer difference NMR.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--highwire.stanford.edu-icons-externalservices-pubmed-sage.gif Related Articles Monomer-collagen interactions studied by saturation transfer difference NMR.
J Dent Res. 2013 Mar;92(3):284-8
Authors: Hiraishi N, Tochio N, Kigawa T, Otsuki M, Tagami J
Abstract
Functional monomers in dentin adhesives are involved in wetting dental substrates, demineralization, and the formation of calcium salts....
nmrlearner
Journal club
0
04-09-2013 06:31 PM
[NMR paper] Multiple quantum filtered NMR studies of the interaction between collagen and water i
Multiple quantum filtered NMR studies of the interaction between collagen and water in the tendon.
Related Articles Multiple quantum filtered NMR studies of the interaction between collagen and water in the tendon.
J Am Chem Soc. 2002 Mar 27;124(12):3125-32
Authors: Eliav U, Navon G
We studied the physical processes and the chemical reactions involved in magnetization transfer between water and large proteins, such as collagen, in bovine Achilles tendon. Since the NMR spectrum for such proteins is broadened by very large dipolar interactions,...
nmrlearner
Journal club
0
11-24-2010 08:49 PM
[NMR paper] Effect of thermal denaturation on water-collagen interactions: NMR relaxation and dif
Effect of thermal denaturation on water-collagen interactions: NMR relaxation and differential scanning calorimetry analysis.
Related Articles Effect of thermal denaturation on water-collagen interactions: NMR relaxation and differential scanning calorimetry analysis.
Biopolymers. 1999 Dec;50(7):690-6
Authors: Rochdi A, Foucat L, Renou JP
The dependence of the proton spin-lattice relaxation rate, and of the enthalpy and temperature of denaturation on water content, were studied by nmr and differential scanning calorimetry (DSC) in native and...
nmrlearner
Journal club
0
11-18-2010 08:31 PM
Exploring collagen self-assembly by NMR.
Exploring collagen self-assembly by NMR.
Related Articles Exploring collagen self-assembly by NMR.
Phys Chem Chem Phys. 2010 Sep 28;
Authors: Lisitza N, Huang X, Hatabu H, Patz S
The time-dependence of the NMR signal intensity of collagen type I is representative of protein aggregation. It is pH sensitive and can be related to aggregation mechanism.
nmrlearner
Journal club
0
09-30-2010 06:54 PM
[NMR paper] NMR study of collagen-water interactions.
NMR study of collagen-water interactions.
Related Articles NMR study of collagen-water interactions.
Biopolymers. 1994 Dec;34(12):1615-26
Authors: Renou JP, Bonnet M, Bielicki G, Rochdi A, Gatellier P
A proton magnetic resonance study of different cross-linked collagens was performed as a function of water content and temperature. Collagens from three connective tissues (calf, steer, and cow) were chosen according to the different number of nonreducible multivalent cross-links, which increases during the life of animal. Samples were hydrated...
nmrlearner
Journal club
0
08-22-2010 03:29 AM
[NMR paper] Cell adhesion promoting peptide GVKGDKGNPGWPGAP from the collagen type IV triple heli
Cell adhesion promoting peptide GVKGDKGNPGWPGAP from the collagen type IV triple helix: cis/trans proline-induced multiple 1H NMR conformations and evidence for a KG/PG multiple turn repeat motif in the all-trans proline state.
Related Articles Cell adhesion promoting peptide GVKGDKGNPGWPGAP from the collagen type IV triple helix: cis/trans proline-induced multiple 1H NMR conformations and evidence for a KG/PG multiple turn repeat motif in the all-trans proline state.
Biochemistry. 1991 Aug 20;30(33):8251-67
Authors: Mayo KH, Parra-Diaz D, McCarthy JB,...
nmrlearner
Journal club
0
08-21-2010 11:12 PM
[NMR paper] Cell adhesion promoting peptide GVKGDKGNPGWPGAP from the collagen type IV triple heli
Cell adhesion promoting peptide GVKGDKGNPGWPGAP from the collagen type IV triple helix: cis/trans proline-induced multiple 1H NMR conformations and evidence for a KG/PG multiple turn repeat motif in the all-trans proline state.
Related Articles Cell adhesion promoting peptide GVKGDKGNPGWPGAP from the collagen type IV triple helix: cis/trans proline-induced multiple 1H NMR conformations and evidence for a KG/PG multiple turn repeat motif in the all-trans proline state.
Biochemistry. 1991 Aug 20;30(33):8251-67
Authors: Mayo KH, Parra-Diaz D, McCarthy JB,...
Collagen connection: The sticky ends
Discovering the secrets of collagen, a major component of connective tissue in mammals could lead to improved tissue engineering and cosmetic and reconstructive medicine. Researchers at Rice University have now used NMR spectroscopy to demonstrate how model collagen fibres self-assemble via their sticky ends.
Linear Mode
