Recent studies have added weight to the idea that amyloid-beta is a causative agent in Alzheimer's disease rather than the plaques formed from these chunks of misfolded peptide that deposit in the diseased brain. Now, European researchers have used REAPDOR solid-state NMR spectroscopy to analyse the hydrogen bonds in the tiny fibrils of amyloid-beta peptide, offering another perspective on this neurodegenerative disorder.
Protein pathways provide clues in leukemia research - R & D Magazine
Protein pathways provide clues in leukemia research - R & D Magazine
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Protein pathways provide clues in leukemia research
R & D Magazine
If it's possible to know the protein signaling pathways of particular types of leukemia, .... of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe.
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06-14-2012 01:45 PM
Protein Structures Give Disease Clues - Bioscience Technology
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Protein Structures Give Disease Clues
Bioscience Technology
Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules â?? potentially leading to new ways to treat ...
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Protein Structures Give Disease Clues - Bioscience Technology
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02-02-2012 09:43 PM
Protein structures give disease clues - PhysOrg.com
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PhysOrg.com
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Protein structures give disease clues
PhysOrg.com
Credit: James Ames, UC Davis Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules -- potentially ...
and more »
Protein structures give disease clues - PhysOrg.com
Protein structures give disease clues - EurekAlert (press release)
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Protein structures give disease clues
EurekAlert (press release)
Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules -- potentially leading to new ways to treat ...
and more »
Protein structures give disease clues - EurekAlert (press release)
More...
[NMR paper] Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside inte
Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment.
Related Articles Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment.
Neurochem Res. 2004 Feb;29(2):447-53
Authors: Mandal PK, Pettegrew JW
Amyloid peptide (Abeta) is the major protein constituent of neuritic plaques in Alzheimer's disease (AD). This peptide is an amphipathic molecule that...
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11-24-2010 09:25 PM
[NMR paper] Amyloid fibril formation by A beta 16-22, a seven-residue fragment of the Alzheimer's
Amyloid fibril formation by A beta 16-22, a seven-residue fragment of the Alzheimer's beta-amyloid peptide, and structural characterization by solid state NMR.
Related Articles Amyloid fibril formation by A beta 16-22, a seven-residue fragment of the Alzheimer's beta-amyloid peptide, and structural characterization by solid state NMR.
Biochemistry. 2000 Nov 14;39(45):13748-59
Authors: Balbach JJ, Ishii Y, Antzutkin ON, Leapman RD, Rizzo NW, Dyda F, Reed J, Tycko R
The seven-residue peptide N-acetyl-Lys-Leu-Val-Phe-Phe-Ala-Glu-NH(2), called A...
Alzheimer's analysed: New clues in brain disease
Recent studies have added weight to the idea that amyloid-beta is a causative agent in Alzheimer's disease rather than the plaques formed from these chunks of misfolded peptide that deposit in the diseased brain. Now, European researchers have used REAPDOR solid-state NMR spectroscopy to analyse the hydrogen bonds in the tiny fibrils of amyloid-beta peptide, offering another perspective on this neurodegenerative disorder.
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