BioNMR - Keystone Symposia Frontiers of NMR in Biology 2011

<table><tbody><tr><td align="center">Organizers: Michael F. Summers, Dorothee Kern and David E. Wemmer
January 8 - 13, 2011 • Big Sky Resort • Big Sky, Montana </td><td align="center">
</td></tr></tbody></table>
Conference website

Meeting Summary

Nuclear magnetic resonance (NMR) spectroscopy is now a well-established tool for determining structures of small to moderate size biomacromolecules. The horizon is expanding, however, through recent methodological advances, including the evolution of approaches that combine NMR with computational, X-ray crystallographic, cryo-electron microscopic, and single molecule methodologies. These have led to unprecedented insights into structure, dynamics, and mechanisms, even in large systems, making NMR a premier tool for studying macromolecular function. This symposium will highlight the latest technological advances in NMR spectroscopy, as well as recent bio-functional discoveries made using these approaches. Emphasis will be placed on systems that challenge the current technology, including high-molecular weights, membrane proteins, folding and dynamics, transient states, and drug discovery. In addition, the symposium will provide a forum for discussions on the needs and efforts to consolidate the best approaches, and on the latest advances and new trends in biological NMR.

Rates and Deadlines listed below are for the 2011-A3 "Frontiers of NMR in Biology" conference only.

*All deadlines end at 12:00 midnight US Mountain Standard Time

<table width="100%" border="1" cellpadding="5" cellspacing="0"> <tbody><tr bgcolor="#dcdcdc"> <td class="SmallerFont">Deadline</td> <td class="SmallerFont">Date</td> <td class="SmallerFont">Cost</td> </tr> <tr> <td class="SmallerFont">Abstract
More details</td> <td class="SmallerFont">Before and On September 15, 2010</td> <td class="SmallerFont">$50.00* USD</td> </tr> <tr> <td class="SmallerFont">Late Abstract
More details</td> <td class="SmallerFont">After September 15, 2010 until October 12, 2010</td> <td class="SmallerFont">$50.00* (abstract fee)
+ $50.00 (late fee)<hr noshade="noshade" size="1">$100.00 (total cost) USD</td> </tr> <tr><td colspan="3" class="SmallerFont" align="center">* Abstract fee deducted from your registration fee when you register for this meeting</td></tr> <tr> <td class="SmallerFont">Scholarship
More details</td> <td class="SmallerFont">September 15, 2010</td> <td class="SmallerFont">n/a</td> </tr> <tr> <td class="SmallerFont">Early NON-STUDENT Registration
More details</td> <td class="SmallerFont">Before and On November 9, 2010</td> <td class="SmallerFont">$695.00 USD</td> </tr> <tr> <td class="SmallerFont">Regular NON-STUDENT Registration
More details</td> <td class="SmallerFont">After November 9, 2010</td> <td class="SmallerFont">$795.00 USD</td> </tr> <tr> <td class="SmallerFont">Early STUDENT Registration
More details</td> <td class="SmallerFont">Before and On November 9, 2010</td> <td class="SmallerFont">$470.00 USD</td> </tr> <tr> <td class="SmallerFont">Regular STUDENT Registration
More details</td> <td class="SmallerFont">After November 9, 2010</td> <td class="SmallerFont">$570.00 USD</td> </tr> </tbody></table>
* Changes in payment type that result in a refund are subject to a processing fee.

Meeting Program

<table border="0" cellpadding="2" cellspacing="0"><tbody><tr><td>http://www.keystonesymposia.org/medi...icon_clock.gif</td> <td> To view program in "24 hour" time (international) click here. </td></tr></tbody></table>

<table border="0" cellpadding="6" cellspacing="0"> <tbody><tr> <th colspan="3" valign="TOP" align="center">Saturday, January 8</th> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 3:00 - 7:30 PM </td> <td class="none" valign="TOP"> Registration </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 6:30 - 7:30 PM </td> <td class="none" valign="TOP"> Refreshments </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 7:30 - 9:30 PM </td> <td valign="TOP"> Keynote Session
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Juli Feigon, University of California, Los Angeles, USA
RNA Structure and Dynamics </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Gerhard Wagner, Harvard Medical School, USA
NMR for Elucidating Biological Mechanisms </td> <td>
</td> </tr> <tr> </tr> <tr> <th colspan="3" valign="TOP" align="center">Sunday, January 9</th> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 7:00 - 8:00 AM </td> <td class="none" valign="TOP"> Breakfast </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 8:00 - 11:00 AM </td> <td valign="TOP"> New Methods for Studying Structure and Dynamics I
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Robert G. Griffin, Massachusetts Institute of Technology, USA
Development and Applications of DNP in Solid State NMR </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Christopher P. Jaroniec, Ohio State University, USA
Paramagnetic Reagents for Protein Structure Determination by Solid State NMR </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Lewis E. Kay, University of Toronto, Canada
New NMR Methods for Studies of Very Large Proteins </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Marcellus Ubbink, Leiden Institute of Chemistry, Netherlands
Paramagnetic Probes for Studying Macromolecular Structure and Interactions </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Short Talk(s) to be Chosen from Abstracts,
</td> <td>
</td> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 9:20 - 9:40 AM </td> <td class="none" valign="TOP"> Coffee Break </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 11:00 AM- 1:00 PM </td> <td class="none" valign="TOP"> Poster Setup </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 1:00 - 10:00 PM </td> <td class="none" valign="TOP"> Poster Viewing </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 4:30 - 5:00 PM </td> <td class="none" valign="TOP"> Coffee Available </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 5:00 - 7:00 PM </td> <td valign="TOP"> Exciting New Results
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Speakers to be Announced,
</td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Short Talk to be Chosen from Abstracts,
</td> <td>
</td> </tr> <tr> </tr> <tr> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 7:00 - 8:00 PM </td> <td class="none" valign="TOP"> Social Hour w/ Lite Bites </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 7:30 - 10:00 PM </td> <td valign="TOP"> Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <th colspan="3" valign="TOP" align="center">Monday, January 10</th> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 7:00 - 8:00 AM </td> <td class="none" valign="TOP"> Breakfast </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 8:00 - 11:00 AM </td> <td valign="TOP"> New Insights into RNA Structure and Dynamics
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Frederic H.T. Allain, ETH Zurich, Switzerland
Protein-RNA Recognition: Structures and Dynamics </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Victoria Manuel D'Souza, Harvard University, USA
RNA Equilibrium that Regulates Read-Through </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Hashim M. Al-Hashimi, University of Michigan, USA
RNA Dynamics and Folding </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Michael F. Summers, University of Maryland Baltimore County and HHMI, USA
New Approaches for NMR Studies of Very Large RNAs </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Short Talk(s) to be Chosen from Abstracts,
</td> <td>
</td> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 9:20 - 9:40 AM </td> <td class="none" valign="TOP"> Coffee Break </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 11:00 AM- 1:00 PM </td> <td class="none" valign="TOP"> Poster Setup </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 1:00 - 10:00 PM </td> <td class="none" valign="TOP"> Poster Viewing </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 2:30 - 4:30 PM </td> <td valign="TOP"> Workshop 1: Advances in Protein Labeling and Preparation
</td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 4:30 - 5:00 PM </td> <td class="none" valign="TOP"> Coffee Available </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 5:00 - 7:00 PM </td> <td valign="TOP"> Protein Folding and Function
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Peter E. Wright, The Scripps Research Institute, USA
Function and Properties of Intrinsically Unfolded Proteins </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Roberto De Guzman, University of Kansas, USA
Structure and Assembly of Bacterial Needles </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> David E. Wemmer, University of California, Berkeley, USA
Application of NMR and Molecular Simulations to A-beta </td> <td>
</td> </tr> <tr> </tr> <tr> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 7:00 - 8:00 PM </td> <td class="none" valign="TOP"> Social Hour w/ Lite Bites </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 7:30 - 10:00 PM </td> <td valign="TOP"> Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <th colspan="3" valign="TOP" align="center">Tuesday, January 11</th> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 7:00 - 8:00 AM </td> <td class="none" valign="TOP"> Breakfast </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 8:00 - 11:00 AM </td> <td valign="TOP"> Interactions at Membranes
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Tatiana G. Kutateladze, University of Colorado Health Sciences Center, USA
Structural Insight into the ‘Histone Code’ Recognition by PHD Fingers </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Katherine A. Henzler-Wildman, Washington University, USA
Mechanistic Studies of Drug Transporter Systems </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Charles R. Sanders, Vanderbilt University School of Medicine, USA
Unraveling Disease Mechanisms Associated with Membrane Proteins Using NMR </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Francesca M. Marassi, Burnham Institute, USA
Structural Studies of Membrane Proteins in Phospholipid Bilayers </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Short Talk(s) to be Chosen from Abstracts,
</td> <td>
</td> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 9:20 - 9:40 AM </td> <td class="none" valign="TOP"> Coffee Break </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 11:00 AM- 1:00 PM </td> <td class="none" valign="TOP"> Poster Setup </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 1:00 - 10:00 PM </td> <td class="none" valign="TOP"> Poster Viewing </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 4:30 - 5:00 PM </td> <td class="none" valign="TOP"> Coffee Available </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 5:00 - 7:00 PM </td> <td valign="TOP"> Drug Targets
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Speaker to be Announced,
</td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Wolfgang S. Peti, Brown University, USA
NMR Studies of Large Intracellular Signaling Complexes </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Speaker to be Announced,
</td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Short Talk to be Chosen from Abstracts,
</td> <td>
</td> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 7:00 - 8:00 PM </td> <td class="none" valign="TOP"> Social Hour w/ Lite Bites </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 7:30 - 10:00 PM </td> <td valign="TOP"> Poster Session 3
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <th colspan="3" valign="TOP" align="center">Wednesday, January 12</th> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 7:00 - 8:00 AM </td> <td class="none" valign="TOP"> Breakfast </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 8:00 - 11:00 AM </td> <td valign="TOP"> Macromolecular Interactions
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Kurt Wüthrich, ETH Zurich/The Scripps Research Institute, Switzerland
Structure-Function Studies of GroEL-GroES </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Kylie J. Walters, University of Minnesota, USA
Mechanistic Insights into Ubiquitin-Dependent Proteolysis </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Tatyana Igumenova, Texas A&M University, USA
Structure and Dynamics of Lipid-Binding Proteins by NMR </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Mitsuhiko Ikura, Ontario Cancer Institute, Canada
Role of NMR in Cancer Cell Signaling Studies </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Short Talk(s) to be Chosen from Abstracts,
</td> <td>
</td> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 9:20 - 9:40 AM </td> <td class="none" valign="TOP"> Coffee Break </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 2:30 - 4:30 PM </td> <td valign="TOP"> Workshop 2: Computational Approaches for Structure Determination
</td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 4:30 - 5:00 PM </td> <td class="none" valign="TOP"> Coffee Available </td> <td class="none" nowrap="nowrap" align="right"> Lower Atrium </td> </tr> <tr> <td class="none" valign="TOP" align="right"> 5:00 - 7:00 PM </td> <td valign="TOP"> New Methods for Studying Structure and Dynamics II
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010 </td> <td class="none" align="right"> Gallatin </td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Marc Baldus, Utrecht University, Netherlands
Advances and Frontiers in Solid State NMR </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Dorothee Kern, Brandeis University, USA
Understanding Function from Dynamics </td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Short Talk to be Chosen from Abstracts,
</td> <td>
</td> </tr> <tr> <td>
</td> <td valign="TOP" align="left"> Ad Bax, NIDDK, National Institutes of Health, USA
Advances and Frontiers in Solution-State NMR </td> <td>
</td> </tr> <tr> </tr> <tr> </tr> <tr> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 7:00 - 8:00 PM </td> <td class="none" valign="TOP"> Social Hour w/ Lite Bites </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> <td nowrap="nowrap" valign="top" align="right"> 8:00 - 11:00 PM </td> <td class="none" valign="TOP"> Entertainment </td> <td class="none" align="right"> Jefferson/Madison </td> </tr> <tr> </tr><tr> <th colspan="3" valign="TOP" align="center">Thursday, January 13</th> </tr> <tr> <td nowrap="nowrap" valign="top" align="right">
</td> <td class="none" valign="TOP"> Departure </td> <td class="none" nowrap="nowrap" align="right">
</td> </tr> <tr><td colspan="3" class="SmallerFont"> *=Session Chair †=Speaker invited, not yet responded. </td></tr></tbody></table>