NMR, alcohols, protein solvation and protein denaturation.
Related Articles NMR, alcohols, protein solvation and protein denaturation.
EXS. 1994;71:261-8
Authors: Wüthrich K
The amino acid side chains of Ser, Thr and Tyr contain the hydroxyl functional group that is characteristic of alcohols, and a variety of different alcohols are used either as structure-inducing or denaturing co-solvents in physical-chemical studies of proteins. This article surveys selected aspects of the influence of protein-intrinsic and -extrinsic hydroxyl groups on studies of the solvation of peptides and proteins by nuclear magnetic resonance (NMR) spectroscopy.
PMID: 8032157 [PubMed - indexed for MEDLINE]
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PubMed