Thread: Question from NMRWiki Q&A forum Varian Biopack pulse sequences for intermolecular NOEs
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Unread 08-22-2010, 02:30 AM
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Default Varian Biopack pulse sequences for intermolecular NOEs
Varian Biopack pulse sequences for intermolecular NOEs

Hi All, I'm trying to set up some experiments to determine intermolecular NOEs in a peptide:protein complex. At the moment from looking at the Biopack library, I have found 4 pulse sequences which will do this and each provide different information (gnoesyNhsqc_CN, gnoesyNhsqc_NN, gnoesyChsqc_CC and gnoesyChsqc_NC). Would people recommend using a combination of all four of these experiments to determine the intermolecular NOEs for use in structure calculations?



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