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Default Protein secondary structure determination by NMR. Application with recombinant human

Protein secondary structure determination by NMR. Application with recombinant human cyclophilin.

Related Articles Protein secondary structure determination by NMR. Application with recombinant human cyclophilin.

FEBS Lett. 1991 Jul 22;285(2):237-47

Authors: Wüthrich K, Spitzfaden C, Memmert K, Widmer H, Wider G

It is a unique trait of the NMR method for protein structure determination that a description of the polypeptide secondary structure can be obtained at an early stage and quite independently of the complete structure calculation. In this paper the procedures used for secondary structure determination are reviewed and placed in perspective relative to the other steps in a complete three-dimensional structure determination. As an illustration the identification of the regular secondary structure elements in human cyclophilin is described.

PMID: 1855591 [PubMed - indexed for MEDLINE]



Source: PubMed
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