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Default NMR studies of interactions of ligands with dihydrofolate reductase.

NMR studies of interactions of ligands with dihydrofolate reductase.

Related Articles NMR studies of interactions of ligands with dihydrofolate reductase.

Biochem Pharmacol. 1990 Jul 1;40(1):141-52

Authors: Feeney J

NMR spectroscopy is a useful technique for studying interactions, conformations and dynamic processes within ligand-protein complexes. Several examples of the application of the method to studies of complexes of anti-folate drugs with their target enzyme, dihydrofolate reductase, are discussed.

PMID: 2196881 [PubMed - indexed for MEDLINE]



Source: PubMed
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