Thread: NMR paper Time-domain signal modelling in multidimensional NMR experiments for estimation of relaxation parameters.
View Single Post
  #1  
Unread 05-06-2019, 04:47 PM
nmrlearner's Avatar
nmrlearner nmrlearner is offline
Senior Member
  
Join Date: Jan 2005
Posts: 23,178
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 0
Downloads: 0
Uploads: 0
Default Time-domain signal modelling in multidimensional NMR experiments for estimation of relaxation parameters.
Time-domain signal modelling in multidimensional NMR experiments for estimation of relaxation parameters.

Related Articles Time-domain signal modelling in multidimensional NMR experiments for estimation of relaxation parameters.

J Biomol NMR. 2019 May 04;:

Authors: Matviychuk Y, Bostock MJ, Nietlispach D, Holland DJ

Abstract
We present a model-based method for estimation of relaxation parameters from time-domain NMR data specifically suitable for processing data in popular 2D phase-sensitive experiments. Our model is formulated in terms of commutative bicomplex algebra, which allows us to use the complete information available in an NMR signal acquired with principles of quadrature detection without disregarding any of its dimensions. Compared to the traditional intensity-analysis method, our model-based approach offers an important advantage for the analysis of overlapping peaks and is robust over a wide range of signal-to-noise ratios. We assess its performance with simulated experiments and then apply it for determination of [Formula: see text],*[Formula: see text], and*[Formula: see text] relaxation rates in datasets of a protein with more than 100 cross peaks.


PMID: 31055682 [PubMed - as supplied by publisher]



More...
Reply With Quote

Did you find this post helpful? Yes | No