Thread: NMR paper Solution NMR Studies of Anesthetic Interactions with Ion Channels.
View Single Post
  #1  
Unread 04-21-2018, 10:14 AM
nmrlearner's Avatar
nmrlearner nmrlearner is offline
Senior Member
  
Join Date: Jan 2005
Posts: 23,184
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 0
Downloads: 0
Uploads: 0
Default Solution NMR Studies of Anesthetic Interactions with Ion Channels.
Solution NMR Studies of Anesthetic Interactions with Ion Channels.

Related Articles Solution NMR Studies of Anesthetic Interactions with Ion Channels.

Methods Enzymol. 2018;603:49-66

Authors: Bondarenko V, Wells M, Xu Y, Tang P

Abstract
NMR spectroscopy is one of the major tools to provide atomic resolution protein structural information. It has been used to elucidate the molecular details of interactions between anesthetics and ion channels, to identify anesthetic binding sites, and to characterize channel dynamics and changes introduced by anesthetics. In this chapter, we present solution NMR methods essential for investigating interactions between ion channels and general anesthetics, including both volatile and intravenous anesthetics. Case studies are provided with a focus on pentameric ligand-gated ion channels and the voltage-gated sodium channel NaChBac.


PMID: 29673534 [PubMed - in process]



More...
Reply With Quote

Did you find this post helpful? Yes | No