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Default bcTol: a highly water-soluble biradical for efficient dynamic nuclear polarization of biomolecules

From The DNP-NMR Blog:

bcTol: a highly water-soluble biradical for efficient dynamic nuclear polarization of biomolecules


Jagtap, A.P., et al., bcTol: a highly water-soluble biradical for efficient dynamic nuclear polarization of biomolecules. Chem Commun (Camb), 2016. 52(43): p. 7020-3.


http://www.ncbi.nlm.nih.gov/pubmed/27161650


Dynamic nuclear polarization (DNP) is an efficient method to overcome the inherent low sensitivity of magic-angle spinning (MAS) solid-state NMR. We report a new polarizing agent (), designed for biological applications, that yielded an enhancement value of 244 in a microcrystalline SH3 domain sample at 110 K.


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