FAT10 to MAD2, do you copy? NMR clues to inflammatory cancer
The interaction between two proteins, FAT10 and MAD2, leads to cancers associated with inflammation, including liver (hepatocellular carcinoma) and colorectal cancers. NMR spectroscopy reveals new clues regarding the structure of FAT10 and might lead to innovative ways to disrupt this unique interaction and perhaps inhibit cancer.
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