NMR Screening in Fragment-Based Drug Design: A Practical Guide.
Related Articles NMR Screening in Fragment-Based Drug Design: A Practical Guide.
Methods Mol Biol. 2015;1263:197-208
Authors: Kim HY, Wyss DF
Abstract
Fragment-based drug design (FBDD) comprises both fragment-based screening (FBS) to find hits and elaboration of these hits to lead compounds. Typical fragment hits have lower molecular weight (