Thread: Effect of DPC concentration on IDP NMR
View Single Post
  #1  
Unread 11-14-2014, 09:56 AM
krishna MP Das krishna MP Das is offline
Junior Member
  
Join Date: Nov 2014
Posts: 1
Points: 12, Level: 1
Points: 12, Level: 1 Points: 12, Level: 1 Points: 12, Level: 1
Level up: 23%, 38 Points needed
Level up: 23% Level up: 23% Level up: 23%
Activity: 1.4%
Activity: 1.4% Activity: 1.4% Activity: 1.4%
NMR Credits: 0
NMR Points: 0
Downloads: 0
Uploads: 0
Default Effect of DPC concentration on IDP NMR
I am working on a protein which has an important function in regulation of Lipid metabolisism, which is found to be functioning in multiple other ways and is beleieved to be an IDP. We are trying to find the structure of this molecule in the presence of DPC micelles. Recently we have got some curious results 1. DPC concentration (actually the molar ratio with the protein) has a huge impact on what you see in the spectra 2. whether you use protonated or deuterated DPC it does not matter so much. Any insights on this?
Reply With Quote

Did you find this post helpful? Yes | No