Thread: NMR paper NMR-based structural characterization of large protein-ligand interactions.
View Single Post
  #1  
Unread 11-24-2010, 08:49 PM
nmrlearner's Avatar
nmrlearner nmrlearner is offline
Senior Member
  
Join Date: Jan 2005
Posts: 23,174
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 0
Downloads: 0
Uploads: 0
Default NMR-based structural characterization of large protein-ligand interactions.
NMR-based structural characterization of large protein-ligand interactions.

Related Articles NMR-based structural characterization of large protein-ligand interactions.

J Biomol NMR. 2002 Feb;22(2):165-73

Authors: Pellecchia M, Meininger D, Dong Q, Chang E, Jack R, Sem DS

Genomic research on target identification and validation has created a great need for methods that rapidly provide detailed structural information on protein-ligand interactions. We developed a suite of NMR experiments as rapid and efficient tools to provide descriptive structural information on protein-ligand complexes. The methods work with large proteins and in particular cases also without the need for a complete three-dimensional structure. We will show applications with two tetrameric enzymes of 120 and 170 kDa.

PMID: 11883777 [PubMed - indexed for MEDLINE]



Source: PubMed
Reply With Quote

Did you find this post helpful? Yes | No